The CRISPR technology involves cut and revise or cut and remove procedure using protein-ribonucleic acid (RNA) complex using proteins like Cas9 and Cpf1.
CRISPR technology involves transcription of spacer sequences into short CRISPR RNAs (crRNA). It is then followed by fusion of crRNA with trans-activating crRNA (tracrRNA) to form small guide RNA (sgRNA), which guide the system to target the desired DNA. Cas9 molecule then acts as molecular scissors and cuts the targeted DNA, knocking down the gene. This initiates the cell repair process and might repair the defect in the genome or insert a new gene for specific phenotype. Researchers also use CRISPR technology for activation of genes, and epigenetic modifications, among others. Price: 4,599.00 USD
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